Our lab is offering an MA/PhD position to lead a cutting-edge, neuroscience study on brain-based biomarkers and mechanisms of psychedelics-assisted psychotherapy for post-traumatic stress disorder (PTSD).
About the Project
The October 7th terror attack and ensuing wars have led to unparalleled rates of PTSD in Israel, with significant personal and societal implications. At the same time, current treatment approaches show only limited success, leaving the needs of many patients unmet.
MDMA-assisted psychotherapy (MAP) has emerged as a promising intervention, integrating this unique psychedelic compound in psychotherapy protocols. By revealing which brain systems respond to MAP, we will be able to improve the efficacy of this treatment and help more people affected by PTSD.
In this study, we will characterize biomarkers and mechanisms of MAP in individuals dealing with PTSD due to the October 7th attack and subsequent wars, through collaborations with several hospitals and organizations.
To achieve this aim, the project integrates multiple levels of analysis:
Brain circuitry: Investigation of threat-related neural circuitry using functional neuroimaging (fMRI), with emphasis on functional activation and connectivity, as candidate biomarkers of PTSD severity and treatment response.
Psychophysiology: Quantification of autonomic threat reactivity (e.g., skin conductance, heart rate/HRV, startle responses) to index defensive responding and its modulation following treatment.
Neuroendocrine systems: Examination of stress- and therapy-relevant hormonal systems, including HPA-axis function (cortisol) and oxytocin dynamics, as potential mediators of therapeutic effects.
Behavioral processes: Objective quantification of aberrant motivational tendencies as core features of PTSD, with a focus on developing computationally tractable behavioral indices linked to clinical outcomes.
Candidate
We are seeking highly motivated MA and PhD students with strong quantitative and analytical backgrounds and a keen interest in integrating clinical and neuroscience perspectives with advanced neuroimaging and psychophysiological methodologies.
Preferred qualifications:
BSc or MSc in Computer Science, Data Science, Computational Neuroscience, Engineering, or a related field
Proven proficiency in programming and data analysis (e.g., independence in Python, MATLAB, or Linux shell scripts)
Experience with experimental platforms (e.g., PsychoPy) and neuroimaging tools (e.g., AFNI, SPM, FSL) is a plus
Opportunity
Students will be embedded in a highly interdisciplinary, supportive research environment, in close collaboration with leading experimental neuroscience groups in Israel and internationally.
The position offers:
Hands-on experience with multimodal clinical neuroscience data (fMRI, psychophysiology, endocrinology, behavior, and more)
Opportunities to lead and contribute to high-impact publications and conference presentations
Involvement in cutting-edge research on PTSD and emerging therapeutic interventions (MDMA-assisted psychotherapy)
Collaboration with international research groups and clinical partners
Competitive stipend and exemption from tuition
Application Process
Interested candidates should submit:
Curriculum vitae (including relevant coursework, research experience, programming experience, and publications if applicable)
Contact information for 2–3 references
Applications should be sent to abendlab2023@gmail.com.
Review of applications will begin immediately and continue until the position is filled.